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Podcast
Published:July 15, 2025
Updated:July 15, 2025
How Do We Put Guardrails on AI? with Shreya Rajpal
Neural Compass Podcast Episode 9

Listen on: Spotify, Apple, or wherever you get your podcasts

Episode Description

In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) speaks with Shreya Rajpal, founder and CEO of Guardrails AI—an open-source pioneer at the forefront of AI safety and infrastructure.

They explore what it really means to make AI reliable, diving into lessons from self-driving cars, the limitations of traditional “accuracy” metrics, and how to build systems that earn human trust. From simulation testing to open-source strategy, Shreya offers a compelling look at what it takes to scale AI safely—and why responsibility starts long before deployment.

This episode touches on:

  • Why reliability is a lifecycle challenge, not just a technical one
  • How simulation testing is reshaping safety in GenAI
  • Why accuracy isn’t the right goal—and what to measure instead
  • How product design and trust go hand in hand
  • The engineering mindset behind building a company
Sources

About Our Guest
Shreya Rajpal is the CEO and founder of Guardrails AI, an open-source platform for ensuring trust and reliability in generative AI applications. Previously, she worked on machine learning for self-driving systems and special projects at Apple. Today, she’s one of the leading voices shaping AI safety and developer experience, with a mission to make scalable, responsible AI the default—not the exception.

About Our Host
Mark Jacobstein is the co-founder and president of Jimini Health. A longtime entrepreneur at the intersection of AI and health tech, he now leads Jimini’s mission to transform mental and behavioral health through clinically grounded, AI-powered care.

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