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Neural Compass
Hosted by Jimini co-founder Mark Jacobstein, each episode features conversations with the scientists, builders, and executives at the frontier of behavioral health and artificial intelligence.
The Science Advanced. The Patients Did Not Get Better, with Dr. Thomas Insel
Newest Episode · July 15, 2026
The Science Advanced. The Patients Did Not Get Better, with Dr. Thomas Insel
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Hosted by Mark Jacobstein

Mark Jacobstein is the co-founder of Jimini Health. He started Neural Compass because the people doing the most important work in mental health are rarely the ones being heard. Each episode is his attempt to fix that. Read Mark's take on Substack

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The Science Advanced. The Patients Did Not Get Better, with Dr. Thomas Insel
July 15, 2026
The Science Advanced. The Patients Did Not Get Better, with Dr. Thomas Insel
AI Meets the Clinic
Rethinking Treatment
The Measuring Gap: How AI and objective data are finally transforming psychiatric care, with Arpan & Amit Parikh
June 4, 2026
The Measuring Gap: How AI and objective data are finally transforming psychiatric care, with Arpan & Amit Parikh
Rethinking Treatment
Care in the Real World
Why Your Brain Functions Like a Specialized Swiss Army Knife, with Michael Platt
June 1, 2026
Why Your Brain Functions Like a Specialized Swiss Army Knife, with Michael Platt
Neuroscience & the Mind
Leadership & Psychology
Why Healthcare, Ever the Tech Laggard, Finally Got the AI Memo, with Jacob Effron
April 7, 2026
Why Healthcare, Ever the Tech Laggard, Finally Got the AI Memo, with Jacob Effron
Founders & Funders
AI Meets the Clinic
“Conversational Doorknobs” & Broken Science with the Funniest Man in Psychology, Adam Mastroianni
March 18, 2026
“Conversational Doorknobs” & Broken Science with the Funniest Man in Psychology, Adam Mastroianni
Behavioral Science
Neuroscience & the Mind
Tech, AI, and the Future of Therapy, with Dr. Harry Ritter, Alma's CEO
February 10, 2026
Tech, AI, and the Future of Therapy, with Dr. Harry Ritter, Alma's CEO
Founders & Funders
Care in the Real World
Can Stress Rewire the Brain—Across a Lifetime? with Dr. Nikolaos Daskalakis
January 6, 2026
Can Stress Rewire the Brain—Across a Lifetime? with Dr. Nikolaos Daskalakis
Neuroscience & the Mind
Rethinking Treatment
Can DNA Data Unlock the Next Era of Medicine? with Dr. Yaniv Erlich
December 16, 2025
Can DNA Data Unlock the Next Era of Medicine? with Dr. Yaniv Erlich
Neuroscience & the Mind
Founders & Funders
 Is this the "Century of the Brain"? with Greg Kubin & Matias Serebrinsky
November 25, 2025
Is this the "Century of the Brain"? with Greg Kubin & Matias Serebrinsky
Founders & Funders
AI Meets the Clinic
Are We Teaching AI to Care—or Just to Sound Like It? with Dr. Nick Haber
November 11, 2025
Are We Teaching AI to Care—or Just to Sound Like It? with Dr. Nick Haber
AI Meets the Clinic
Rethinking Treatment
What Does It Take To Reform Mental Health Care From The Inside Out? with Mike Kopko
November 4, 2025
What Does It Take To Reform Mental Health Care From The Inside Out? with Mike Kopko
Founders & Funders
Care in the Real World
Could Ketamine Unlock a New Era in Mental Health? with Dr. John Krystal
October 28, 2025
Could Ketamine Unlock a New Era in Mental Health? with Dr. John Krystal
Neuroscience & the Mind
Rethinking Treatment
How Do We Deliver Better Mental Health Care At Scale? with Dr. Stephanie Eken
October 22, 2025
How Do We Deliver Better Mental Health Care At Scale? with Dr. Stephanie Eken
Rethinking Treatment
Care in the Real World
Is the Brain More Flexible Than We Ever Imagined? with David Eagleman
October 16, 2025
Is the Brain More Flexible Than We Ever Imagined? with David Eagleman
Neuroscience & the Mind
Behavioral Science
How can we design mental health tools people actually use and trust? with Stephen Duke
August 29, 2025
How can we design mental health tools people actually use and trust? with Stephen Duke
Care in the Real World
Founders & Funders
What if "Crushing It" is Crushing You? with Jerry Colonna
August 7, 2025
What if "Crushing It" is Crushing You? with Jerry Colonna
Leadership & Psychology
Behavioral Science
What If AI Could Help Us Save Lives? with Dr. Seth Feuerstein
July 22, 2025
What If AI Could Help Us Save Lives? with Dr. Seth Feuerstein
AI Meets the Clinic
Rethinking Treatment
How Do We Put Guardrails on AI? with Shreya Rajpal
July 15, 2025
How Do We Put Guardrails on AI? with Shreya Rajpal
AI Meets the Clinic
Founders & Funders
How is Machine Learning Improving the How, What, and When of Cancer Diagnosis? with Dr. Adam Yala
July 1, 2025
How is Machine Learning Improving the How, What, and When of Cancer Diagnosis? with Dr. Adam Yala
AI Meets the Clinic
Neuroscience & the Mind
What Happens When You Believe In AI Before Everyone Else? with Yan-David “Yanda” Erlich
June 24, 2025
What Happens When You Believe In AI Before Everyone Else? with Yan-David “Yanda” Erlich
Neuroscience & the Mind
Founders & Funders
Why Can’t Mental Health Innovations Reach the People Who Need Them Most? with Dr. Amber Childs
June 17, 2025
Why Can’t Mental Health Innovations Reach the People Who Need Them Most? with Dr. Amber Childs
Rethinking Treatment
Neuroscience & the Mind
What Happens When a Patient Works with Both a Therapist and AI? with Jon Tippins
June 10, 2025
What Happens When a Patient Works with Both a Therapist and AI? with Jon Tippins
Care in the Real World
Behavioral Science
Can I Trust an AI Therapist? with Dr. Lyle Ungar
May 27, 2025
Can I Trust an AI Therapist? with Dr. Lyle Ungar
AI Meets the Clinic
Behavioral Science
Beyond Placebo: Is the Brain Our Most Powerful Medicine? with Dr. Asya Rolls
May 27, 2025
Beyond Placebo: Is the Brain Our Most Powerful Medicine? with Dr. Asya Rolls
Neuroscience & the Mind
Rethinking Treatment
Are We Treating Anxiety While Ignoring Avoidance? with Dr. Luana Marques
May 27, 2025
Are We Treating Anxiety While Ignoring Avoidance? with Dr. Luana Marques
Rethinking Treatment
Behavioral Science
Podcast Guests
Guests include leading researchers, investors, and executives at the frontier of behavioral health & AI
New episodes every two weeks.

For healthcare executives, researchers, investors, and anyone who thinks the mental health crisis deserves serious answers — this is the show.

Jimini

If you are experiencing a mental health crisis please reach out to 988 for free and confidential support 24/7. You can call or text 988 or chat at https://988lifeline.org. If you are experiencing a life threatening emergency, please call 911 or go to your nearest emergency room.

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