Episode Description
In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Dr. Seth Feuerstein, Founder & CEO of Oui Therapeutics and Yale faculty member. Together, they unpack a striking insight: that much of what we think we know about suicide is wrong—and that misperception is blocking progress. Drawing on decades of clinical, academic, and entrepreneurial experience, Dr. Feuerstein shares a new model for understanding suicidality, why data-backed interventions are often ignored, and how to bring innovation into a mental health system resistant to change.
This episode touches on:
- Why suicide isn’t just a symptom of depression—and what it really is
- A behavioral approach that reduces suicide attempts by 60%
- How shame, access, and outdated care models hold patients back
- The opportunity (and risk) of AI-powered therapy
- Why scaling digital mental health starts with better incentives
About the Speakers
Seth Feuerstein, Guest
is a psychiatrist who has spent the last three decades innovating in healthcare and biomedical sciences. Through combined medical and law degrees, his focus has been addressing gaps in care and equity in access to quality treatment. He is the founder and CEO of Oui Therapeutics and has advised major health systems and startups on digital mental health strategy. A longtime advocate for data-driven, scalable care, his work bridges clinical insight with real-world implementation.
Mark Jacobstein is the co-founder and president of Jimini Health. A longtime entrepreneur at the intersection of AI and health tech, he now leads Jimini’s mission to transform mental and behavioral health through clinically grounded, AI-powered care.
For healthcare executives, researchers, investors, and anyone who thinks the mental health crisis deserves serious answers — this is the show.